Presenter: Associate Professor Matthew Pase
Abstract: Sleep disturbances are commonly observed in dementia patients. As dementia and neurodegeneration can cause profound sleep disturbance, sleep disorders occurring just before dementia onset may be part of dementia’s natural history. However, several mechanisms point towards poor sleep as a dementia risk factor, with poor sleep linked to neuroinflammation, blood-brain barrier permeability, reduced synaptic plasticity and memory consolidation, hypoxic brain injury, and disrupted glymphatic clearance of neurotoxic brain waste. This talk will highlight Matthew Pase's recent work investigating poor sleep as a dementia risk factor.
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Tue 14 Nov 2023, 12:00 PM - 1:00 PM
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Created 12th October 2023
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